CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 520 enrolled
Drug / intervention
Antipsychotic use +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05686772
NCT05686772N/ACompleted

A Better Understanding of the Association Between Problem Gambling and Psychotic Disorders in Young Adults: a New Path Towards Recovery

Laval University·observational·Posted Jan 17, 2023·Updated May 28, 2025

In Brief

An observational study evaluating Antipsychotic use, Psychiatric comorbidities, and 3 other interventions for Gambling Disorder and Psychotic Disorders. Completed, enrolled 520 participants across 2 sites.

Detailed Summary

The aims of this propsective cohort study are to get a better understanding of the association between problem gambling and psychotic disorders among young adults with first-episode psychosis. The main questions to be answered are: 1. What is the incidence of problem gambling in this population? 2. What are the predictors of problem gambling in this population? To do so, putative predictors of problem gambling will be analyzed using Cox regression models: * Sociodemographics (e.g., age, gender identity, ethnicity, level of education, employment); * Psychiatric comorbidities (e.g., substance use disorders, cluster B personality disorders); * Antipsychotic use (first/second-generation, third-generation \[aripiprazole, brexpiprazole, cariprazine\]); * Prior gambling history.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesCanada

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJan 17, 2023
Enrollment StartNov 1, 2019
Primary CompletionMay 1, 2023
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 3.5 years ago

Interventions

Antipsychotic usedrug

Use of first/second generation antipsychotics, use of third-generation antipsychotics, use of aripiprazole specifically

Psychiatric comorbiditiesother

Substance use disorders, cluster B personality disorders, anxiety disorder, major depressive disorder, attention-deficit/hyperactivity disorder, tobacco smoking

Sociodemographics/socioeconomic statusother

Age, gender identity, ethnicity, highest educational attainment, employment, at school, homelessness, in a relationship

Gambling historyother

Non-problematic gambling at the time of admission and/or previous 12 months

Clinical variablesother

Main psychiatric diagnosis, history of psychiatric hospitalizations, severity of illness (CGI-S), functioning (SOFAS), concomitant psychotropic medications use