CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 37 enrolled
Drug / intervention
Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT) +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05690555
NCT05690555N/ACompleted

A Randomized Trial Comparing Perioperative Pelvic Floor Physical Therapy to Current Standard of Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation

The Cleveland Clinic·interventional·Posted Jan 19, 2023·Updated Jul 15, 2025

In Brief

A clinical study evaluating Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT), No Pelvic Floor Physical Therapy (PFPT), and 1 other intervention for Pelvic Floor Disorders. Completed, enrolled 37 participants across 1 site.

Detailed Summary

Currently, perioperative pelvic floor physical therapy (PFPT) is not standard of care for all patients who undergo vaginoplasty surgery. While some practices have implemented these new programs, and the above data exist on outcomes associated with perioperative PFPT in transgender women undergoing vaginoplasty, no study has compared implementation of perioperative PFPT to routine care (no perioperative PFPT). Therefore, the primary objective of this study was to compare the effectiveness of postoperative PFPT compared to no PFPT in transgender women undergoing vaginoplasty surgery for gender affirmation. Secondary objectives of the study are 1) to describe the incidence of preoperative pelvic floor dysfunction in transgender women undergoing PFPT and 2) to compare the effectiveness of postoperative PFPT alone to pre- and postoperative PFPT in these patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJan 19, 2023
Enrollment StartSep 25, 2020
Primary CompletionSep 11, 2022
Study CompletionDec 31, 2022
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 3.5 years ago

Interventions

Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT)other

Patients will present to see the physical therapist 3 weeks and 6 weeks postoperatively. The following interventions will be performed: 3 weeks: * Subjective assessment of bowel and bladder function * Visual and external palpation and assessment of external pelvic floor region * Intravaginal pelvic floor assessment * Pelvic floor muscle dynamics and coordination assessment * Instruction of pelvic floor coordination and lengthening * Discussion of dilator program and progression * Home program with instructions 6 weeks: * External scar assessment and treatment if tissue healing allows * Instruction to patient of scar mobilizations * Intravaginal pelvic floor assessment and treatment if indicated * Review of pelvic floor lengthening and coordination * Review and progression of dilator program if appropriate * Assessment of current bowel/bladder symptoms; home program and instructions to address these symptoms

No Pelvic Floor Physical Therapy (PFPT)other

Patients will present to see the physical therapist 3 weeks postoperatively. The following interventions will be performed: Subjective assessment of bowel and bladder function. Visual and external palpation and assessment of external pelvic floor region. Intravaginal pelvic floor assessment. Pelvic floor muscle dynamics and coordination assessment. Review of pelvic floor anatomy and function.

Postoperative PFPTother

Preoperative Diaphragmatic breathing Discuss dilator positioning/introduce dilator program External pelvic floor assessment Teach pelvic floor coordination Current bowel/bladder symptoms; home program and instructions 3 weeks Assessment of bowel and bladder function Visual and external palpation and assessment of external pelvic floor region Intravaginal pelvic floor assessment Pelvic floor muscle dynamics and coordination assessment Instruction of pelvic floor coordination and lengthening Discussion of dilator program and progression Home program with instructions 6 weeks External scar assessment and treatment if tissue healing allows Instruction to patient of scar mobilizations Intravaginal pelvic floor assessment and treatment if indicated Review of pelvic floor lengthening and coordination Review and progression of dilator program if appropriate Current symptoms; home program and instructions