CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Hypnotic Relaxation Intervention (HRI) +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05692960
NCT05692960N/ACompleted

Women's Interventions for Sexual Health: WISH, A Pilot Study

The University of Tennessee, Knoxville·interventional·Posted Jan 20, 2023·Updated Mar 19, 2025

In Brief

A clinical study evaluating Hypnotic Relaxation Intervention (HRI) and Vulvovaginal Atrophy (VVA) for Sexual Dysfunction, Physiological and 2 related conditions. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The overall objective of this program of research is to improve sexual health outcomes for women diagnosed with breast cancer. Our team is developing a multi-component intervention for the four key predictors of sexual health in female cancer survivors: self-image, vulvovaginal tissue quality and symptoms, desire/energy, and relationship-partner concerns. This proposal begins the proof-of-concept pilot study in women with a history of breast cancer to deliver a multi-component intervention to improve vulvo-vaginal atrophy with a vaginal moisturizer, and sexual energy and self-image with a mind-body intervention that involves relaxation and subconscious suggestions with a hypnotic induction delivered via audio file. The primary outcome will be to evaluate the feasibility and acceptability of a multi-component intervention for sexual function. It is hypothesized that at least eighty percent of randomized participants will complete the study without differential withdraws from the control group.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedJan 20, 2023
Enrollment StartFeb 15, 2023
Primary CompletionFeb 9, 2024
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 3.4 years ago

Interventions

Hypnotic Relaxation Intervention (HRI)other

HRI is a combination intervention (Replens™ vaginal moisturizer device and hypnotic relaxation behavioral intervention)

Vulvovaginal Atrophy (VVA)device

VVA is a standard of care intervention (Replens™ vaginal moisturizer device)