CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 100 enrolled
Drug / intervention
Ibuprofen 800 mg +1 moredrug
Likely dose
Ibuprofen 800 mgfrom record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05695664
NCT05695664Early Ph 1Completed
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Comparison of the Postoperative Analgesic Effects of Ibuprofen Versus Ketorolac in Patients Undergoing Orthopedic Surgery

Benazir Bhutto Hospital, Rawalpindi·interventional·Posted Jan 25, 2023·Updated Jan 25, 2023

In Brief

A Early Phase 1 clinical trial evaluating Ibuprofen 800 mg and Ketorolac Injection for Intravenous Drug Usage and 4 related conditions. Completed, enrolled 100 participants across 1 site.

Detailed Summary

Objectives: To compare the postoperative analgesic effects of ibuprofen versus ketorolac in patients undergoing orthopedic surgery at Combined Military Hospital, Rawalpindi. Study design: Randomized controlled trial Setting: Department of Anasthesiology, Combined military Hospital, Rawalpindi Duration of study:6 months (01st August 2021 to 31st January 2022) Material and methods: After ethical approval, 100 patients in randomly divided two equal groups (A and B) were selected. In group A, 800 mg IV ibuprofen while in group B, 30 mg IV ketorolac was given within 30 min of skin closure after orthopedic surgery. The pain was assessed via visual analogue scale postoperatively. The SPSS version 25 was used for analysis of data. P value ≤ 0.05 was considered as significant.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntravenous Drug Usage, Ibuprofen, Ketorolac, Knee Arthroscopy, Postoperative Pain
CountriesPakistan
CollaboratorsCombined Military Hospital, Pakistan

Timeline

Early Ph 1CompletedFinished
20222023202420252026
First PostedJan 25, 2023
Enrollment StartAug 1, 2021
Primary CompletionJan 31, 2022
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 3.4 years ago

Interventions

Ibuprofen 800 mgdrug

Intravenous injection of ibuprofen 800 mg

Ketorolac Injectiondrug

Intravenous injection of Ketorolac 30 mg