At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Triple Prevention Against Cutibacterium Acnes Using Benzoyl Peroxide Preparation in Addition to Pre-operative Cutaneous and Subcutaneous Iodine in Shoulder Surgery; a Single-blinded, Randomized, Controlled Trial.
In Brief
A clinical study evaluating Subcutaneous disinfection and Benzoyl peroxide preparation for Post-Operative Wound Infection and Surgical Site Infection. Completed, enrolled 156 participants across 1 site.
Detailed Summary
Patients planned for shoulder surgery will be identified and contacted for participation. After informed consent is provided, patients will be randomised into one of three groups: pre-operative cutaneous disinfection with iodine (control group), pre-operative cutaneous and subcutaneous disinfection with iodine (double prevention), and pre-operative cutaneous and subcutaneous disinfection with iodine combined with a skin preparation protocol with benzoyl peroxide gel in the days prior to surgery (triple prevention). Bacterial cultures will be collected during surgery of the surgical field and tissue layers. Culture positivity for Cutibacterium Acnes will be compared between the groups as a primary outcome.
Study Details
Timeline
Interventions
After incision, the subcutaneous tissue will be disinfected for 60 seconds using iodine before continuing the surgical approach.
In the days prior to surgery, the skin will be prepared using Benzoyl Peroxide gel according to a standardised protocol.