CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Stimuliother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05701748
NCT05701748N/ACompleted
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EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers

Children's Hospital of Philadelphia·interventional·Posted Jan 27, 2023·Updated Jan 29, 2025

In Brief

A clinical study evaluating Stimuli for Electroencephalography Spectral Edge Frequency and Anesthetic Depth. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The goal of this study is monitor anesthetic depth of children undergoing propofol anesthesia using electroencephalography (EEG). The main questions it aims to answer are: 1. EEG spectral edge frequency (SEF95) readings where 50% of patients do not respond to three stimuli. 2. The propofol blood concentration that corresponds to each of the three EEG SEF95 readings Participants will undergo EEG monitoring, stimuli (placement of oral pacifier, electrical stimulation, and laryngoscopy), and blood collection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsElectroencephalography Spectral Edge Frequency, Anesthetic Depth
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJan 27, 2023
Enrollment StartFeb 3, 2023
Primary CompletionDec 31, 2024
Study CompletionJan 1, 2025
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 3.4 years ago

Interventions

Stimuliother

placement of oral pacifier, electrical stimulation, and laryngoscopy