CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,369 enrolled
Drug / intervention
Label with text health warning +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05714982
NCT05714982N/ACompleted

Randomized Clinical Trial Evaluating the Impact of E-cigarette Device Warnings

UNC Lineberger Comprehensive Cancer Center·interventional·Posted Feb 6, 2023·Updated Sep 12, 2025

In Brief

A clinical study evaluating Label with text health warning, Label with pictorial health warning, and 1 other intervention for Vaping Behaviors. Completed, enrolled 1,369 participants across 1 site.

Detailed Summary

The purpose of this randomized clinical trial is to determine whether e-cigarette warnings increase intentions to quit vaping without the unintended consequence of pushing users toward smoking. This trial addresses these issues by evaluating the impact of e-cigarette warnings by randomly assigning vapers to have their devices and refills labeled with control messages, text warnings, or pictorial warnings. Participants will be US adult (ages 21+) vapers. The trial expects \~1,200 participants to complete Visits 1, 3, and 5.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 6, 2023
Enrollment StartFeb 23, 2023
Primary CompletionJul 23, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 3.4 years ago

Interventions

Label with text health warningother

Labels with e-cigarette health warning that include text about health harms of vaping will be applied to participants' vaping devices and refills. At Visit 1, devices and refills will be labeled with 2 warnings based on their assigned trial arm; at Visit 3, they will get 2 additional warnings based on their assigned trial arm. The order of the 4 labels within this trial arm will be randomized using a Latin square design. Study investigators developed the text and design of these labels.

Label with pictorial health warningother

Labels with e-cigarette health warning that include the same text about health harms of vaping and corresponding pictorial images will be applied to participants' vaping devices and refills. At Visit 1, devices and refills will be labeled with 2 warnings based on their assigned trial arm; at Visit 3, they will get 2 additional warnings based on their assigned trial arm. The order of the 4 labels within this trial arm will be randomized using a Latin square design. Study investigators developed the text and design of these labels.

Label with neutral statements about vapingother

Labels with neutral statements about vaping will be applied to participants' vaping devices and refills. At Visit 1, devices and refills will be labeled with 2 statements based on their assigned trial arm; at Visit 3, they will get 2 additional statements based on their assigned trial arm. The order of the 4 labels within this trial arm will be randomized using a Latin square design. Study investigators developed the text and design of these labels.