At a glance
ClinicalIndex Comparison Record- ✓Age 18-60 years
- ✓Meet DSM-5 criteria for at least moderate Cannabis Use Disorder with use of at least 20 out of the last 28 days
- ✓Positive urine drug screen for cannabis at enrollment visit confirming regular use
- ✓Express a desire to reduce cannabis use or quit
- ✕Pregnant or breastfeeding
- ✕Moderate or severe use disorder of any substance other than tobacco/nicotine
- ✕History of or current psychotic disorder or bipolar disorder
- ✕Active suicidal ideation or suicide attempt within past 180 days
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Preliminary Investigation of Two Repetitive Transcranial Magnetic Stimulation (rTMS) Strategies to Treat Cannabis Use Disorder
In Brief
A clinical study evaluating Repetitive Transcranial Magnetic Stimulation (rTMS) for Cannabis Use Disorder. Completed, enrolled 22 participants across 1 site.
Detailed Summary
In this trial we will work with a group of participants who are having problems related to marijuana use (they have Cannabis Use Disorder) and who want to reduce the amount of marijuana they use or quit using marijuana completely. We are testing to see if a treatment called repetitive transcranial magnetic stimulation (rTMS) can help them achieve that goal when combined with a brief three-session counseling therapy. Participants will receive rTMS to one of two different parts of the brain (the dorsolateral prefrontal cortex--the DLPFC or the ventromedial prefrontal cortex--the vmPFC) to see if applying rTMS to one brain area is more helpful than the other brain area.
Study Details
Timeline
Interventions
Patterned pulsed magnetic stimulation delivered using an electromagnet. We will use a MagVenture rTMS device and a Cool-B65 coil.