CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,200 enrolled
Drug / intervention
Standard Pay-it-forward +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05723263
NCT05723263N/ACompleted
CompareCT.gov

IGHID 12118 - Pay-it-forward Gonorrhea and Chlamydia Testing Among Men in China: The PIONEER Pragmatic Randomized Controlled Trial

University of North Carolina, Chapel Hill·interventional·Posted Feb 10, 2023·Updated Dec 3, 2025

In Brief

A clinical study evaluating Standard Pay-it-forward, Community Engaged Pay-it-forward, and 1 other intervention for Gonorrhea and Chlamydia. Completed, enrolled 1,200 participants across 1 site.

Detailed Summary

PIONEER is a three-arm, programmatic cluster randomized controlled trial (RCT) to compare effectiveness of three implementation strategies, followed by a mixed-methods implementation evaluation study

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGonorrhea, Chlamydia
CountriesChina
CollaboratorsNational Institute of Allergy and Infectious Diseases (NIAID)

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 10, 2023
Enrollment StartApr 1, 2023
Primary CompletionJul 15, 2024
Study CompletionSep 30, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.4 years ago

Interventions

Standard Pay-it-forwardbehavioral

400 men who have sex with men (MSM) at 4 clinics will be enrolled. The standard pay-it-forward arm will include free point-of-care gonorrhea testing, as well as a passive community engagement component (such as viewing postcards and materials written by others encouraging gonorrhea/chlamydia testing).

Community Engaged Pay-it-forwardbehavioral

400 MSM at 4 clinics will be enrolled. The community engaged pay-it-forward arm will include free point-of-care gonorrhea testing, as well as an active community engagement component (such as multi-stakeholder co-creation activities to develop essential components of the intervention and implementation strategies; writing postcards; designing fans with stickers; sending out testing promotion messages on social media; and opportunity to donate to support others)

Control armother

400 MSM at 4 clinics will be enrolled. The control arm will include a fee-based point-of-care gonorrhea testing (approximately 20 U.S. Dollars (USD) per test) and no community engagement component