At a glance
ClinicalIndex Comparison RecordN/ACompleted· 75 enrolled
Drug / intervention
Biogaia L. reuteri Prodentis® lozenges +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients: Prospective Randomized Controlled Trial
In Brief
A clinical study evaluating Biogaia L. reuteri Prodentis® lozenges and Hersheyland Ice Breakers Mints sugar free lozenges for White Spot Lesion. Completed, enrolled 75 participants across 1 site.
Detailed Summary
The goal of this randomized clinical trial was to investigate the effect of probiotic lozenges on the development of white spot lesions (WSLs) compared to a positive control, and no treatment.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsWhite Spot Lesion
CountriesJordan
Collaborators--
Timeline
N/ACompletedFinished
20222023202420252026
Enrollment StartFeb 2022
Primary CompletionJul 2022
Study CompletionDec 2022
First PostedFeb 2023
TodayJul 2026
First PostedFeb 22, 2023
Enrollment StartFeb 14, 2022
Primary CompletionJul 1, 2022
Study CompletionDec 1, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 3.4 years ago
Interventions
Biogaia L. reuteri Prodentis® lozengesdietary
Participants were instructed to use the lozenges twice daily after brushing their teeth; once in the morning and once in the evening
Hersheyland Ice Breakers Mints sugar free lozengesdietary
Hersheyland Ice Breakers Mints sugar free lozenges