CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 47 enrolled
Drug / intervention
Transdiagnostic cognitive behavioral therapy (CBT) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05738967
NCT05738967N/ACompleted
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Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents

Baylor College of Medicine·interventional·Posted Feb 22, 2023·Updated Jul 23, 2025

In Brief

A clinical study evaluating Transdiagnostic cognitive behavioral therapy (CBT) and Treatment as usual for Anxiety and 3 related conditions. Completed, enrolled 47 participants across 1 site.

Detailed Summary

This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety, Depression, Emotional Disorder, Autism
CountriesUnited States
CollaboratorsTexas Higher Education Coordinating Board

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 22, 2023
Enrollment StartMar 15, 2023
Primary CompletionMay 31, 2025
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 3.4 years ago

Interventions

Transdiagnostic cognitive behavioral therapy (CBT)behavioral

Adolescent-caregiver dyads will will participate in CBT focused on exposure therapy and behavioral activation. It will also include flexible incorporation of emotion-focused coping and adaptations for autism.

Treatment as usualbehavioral

Adolescent-caregiver dyads will participate in coordinated referrals to the community. They may receive psychotherapy and/or initiate or change current psychiatric medication (if applicable).