CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 300 enrolled
Drug / intervention
Chlorhexidine gluconate impregnated bordered polyurethane dressing +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05741866
NCT05741866N/ACompleted
CompareCT.gov

Protect PIVCs: An Adaptive Randomized Controlled Trial of a Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs).

The University of Queensland·interventional·Posted Feb 23, 2023·Updated May 20, 2026

In Brief

A clinical study evaluating Chlorhexidine gluconate impregnated bordered polyurethane dressing and Standard bordered polyurethane dressing for Vascular Access Complication and 11 related conditions. Completed, enrolled 300 participants across 3 sites in 2 countries.

Detailed Summary

The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards. The main questions it aims to answer are: * Study Feasibility * Occurrence of infectious complications related to the PIVC Participants will be randomly allocated to receive either of the below dressings to cover and secure their PIVC: * The standard dressing used at their hospital, or * The intervention dressing which has Chlorhexidine gluconate (CHG) on it Researchers will compare standard and CHG dressings to see if the presence of CHG improves the occurrence of infectious complications related to the PIVC.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVascular Access Complication, Device Related Infection, Device Related Sepsis, Device Site Reactions, Catheter Infection, Catheter Complications, Catheter-Related Infections, Catheter Related Complication, Occlusive Dressings, Wound Infection, Wound of Skin, Wound
CountriesAustralia, France
CollaboratorsQueensland Children's Hospital, Royal Brisbane and Women's Hospital, Poitiers University Hospital, Griffith University

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 23, 2023
Enrollment StartMay 3, 2023
Primary CompletionJun 3, 2024
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 3.4 years ago

Interventions

Chlorhexidine gluconate impregnated bordered polyurethane dressingdevice

PIVCs will be dressed and secured at the participating sites * RBWH and PUH: PIVCs will be dressed with Tegaderm™ Antimicrobial I.V. Advanced Securement (9132) dressing and secured with non-sterile tape over extension tubing. * QCH: PIVCs will be dressed with Tegaderm™ Antimicrobial I.V. Advanced Securement (9132) dressing and secured with tubular bandage +/- arm board and non-sterile stretchy tape if PIVC over flexible joint, +/- tissue adhesive as per clinician preference.

Standard bordered polyurethane dressingdevice

PIVCs will be dressed and secured as per standard practice at the participating sites * RBWH and PUH: Bordered polyurethane dressing (Tegaderm™ IV Advanced 1683) and non-sterile tape strip over extension tubing. * QCH: Bordered polyurethane dressing (Tegaderm™ IV Advanced 1682 or 1683) and secured with tubular bandage +/- arm board and non-sterile stretchy tape if PIVC over flexible joint, +/- tissue adhesive as per clinician preference.