At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 16 enrolled
Drug / intervention
PF-07081532 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A PHASE 1, OPEN-LABEL, FIXED-SEQUENCE STUDY TO EVALUATE THE EFFECT OF ITRACONAZOLE AND CYCLOSPORINE ON THE SINGLE-DOSE PHARMACOKINETICS OF PF-07081532 IN OVERWEIGHT OR OBESE ADULT PARTICIPANTS
In Brief
A Phase 1 clinical trial evaluating PF-07081532, Cyclosporine, and 1 other intervention for Healthy. Completed, enrolled 16 participants across 1 site.
Detailed Summary
This is a Phase 1, open-label, fixed-sequence, 3-period study to evaluate the effect of multiple doses of itraconazole and a single dose of cyclosporine on the single-dose PK of PF-07081532 in otherwise healthy, overweight or obese, adult female and male participants. The 3 study periods will be conducted consecutively without a break.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--
Timeline
Phase 1CompletedFinished
202420252026
Enrollment StartFeb 2023
First PostedFeb 2023
Primary CompletionMay 2023
TodayJul 2026
First PostedFeb 27, 2023
Enrollment StartFeb 22, 2023
Primary CompletionMay 29, 2023
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3.3 years ago
Interventions
PF-07081532drug
Oral Tablet
Cyclosporinedevice
Oral Solution
Itraconazoledrug
Oral Capsule