CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 35 enrolled
Drug / intervention
Firefighting training exercises with no fire +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05753254
NCT05753254N/ACompleted

Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Activities - a Study Under Different Training Methods

National Research Centre for the Working Environment, Denmark·interventional·Posted Mar 3, 2023·Updated Aug 6, 2025

In Brief

A clinical study evaluating Firefighting training exercises with no fire, Firefighting training exercises under wood fire, and 1 other intervention for Reactive Hyperemia and 5 related conditions. Completed, enrolled 35 participants across 2 sites.

Detailed Summary

Epidemiological studies based on Danish registries have observed that Danish male firefighters have more cardiovascular disease, infertility diagnose and a trend to increased risk of cancer than other Danish employed males. Firefighting activities include a combination of stressors such as strenuous work under heat, smoke and soot known to be able to affect cardiovascular and reproductive health, with smoke and soot also being known to increase the risk of cancer. The training facilities of real-fire extinguishing exercises in Denmark operate using wood or natural gas fire, which will have differential gradients of smoke, soot and possibly heat. The investigators will use different training conditions to create gradients of the different stressors and investigate health effects thereof. With this approach, the investigators expect to be able to evaluate the individual contribution of the different stressors in markers of cardiovascular, cancer and reproductive health risk. The project will include approx. 35 young conscript participants on a firefighting course, followed in four sessions, three firefighting training sessions under different fire conditions (no fire, wood fire and gas fire) and one control scenario.

Study Details

Timeline

N/ACompletedFinished
202420252026
First PostedMar 3, 2023
Enrollment StartMar 10, 2023
Primary CompletionJul 5, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.3 years ago

Interventions

Firefighting training exercises with no fireother

The participants will be performing firefighting equivalent work in a clean environment, without fire (no ambient temperature, soot or smoke).

Firefighting training exercises under wood fireother

The participants will be in teams performing pre-defined tasks (knocking down the fire, moving heavy objects, and searching and rescuing metal stand in models), under wood fire conditions.

Firefighting training exercises under gas fireother

The participants will be in teams performing pre-defined tasks (knocking down the fire, moving heavy objects, and searching and rescuing metal stand in models), under gas fire conditions.