CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 46 enrolled
Drug / intervention
Imagingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05762679
NCT05762679N/ACompleted
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Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management

Johns Hopkins University·interventional·Posted Mar 10, 2023·Updated Jul 9, 2025

In Brief

A clinical study evaluating Imaging for Myofascial Dysfunction. Completed, enrolled 46 participants across 1 site.

Detailed Summary

The purpose of this study is to quantify the extent of GlycosAminoGlycan/Hyaluronic Acid (GAG/HA) accumulation using T1rho (T1ρ) MRI in the paretic versus non-paretic shoulder rotator muscles, and correlate the T1ρ Magnetic Resonance Imaging (MRI) measurements with US echo texture measurements to develop a clinic-friendly tool to infer the extent of HA accumulation; and to distinguish between latent versus active Post Stroke Shoulder Pain (PSSP) using ultrasound (US) shear strain mapping of the same muscles on the paretic side compared with the non-paretic side.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMyofascial Dysfunction
CountriesUnited States
CollaboratorsNational Center for Complementary and Integrative Health (NCCIH), New York University, George Mason University

Timeline

N/ACompletedFinished
202420252026
First PostedMar 10, 2023
Enrollment StartFeb 28, 2023
Primary CompletionMay 24, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.3 years ago

Interventions

Imagingother

Phase 1 is an imaging biomarker study.