CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 101 enrolled
Drug / intervention
3M™ Clinpro™ Fluoride Aqueous Solution +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05768373
NCT05768373N/ACompleted

Clinical Evaluation of Clinpro™ 2.1% Sodium Fluoride Aqueous Solution in the Treatment of Dentin Hypersensitivity

Solventum US LLC·interventional·Posted Mar 14, 2023·Updated Feb 7, 2025

In Brief

A clinical study evaluating 3M™ Clinpro™ Fluoride Aqueous Solution and 3M™ Vanish™ for Dentin Hypersensitivity. Completed, enrolled 101 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to evaluate the effect of 3M™ Clinpro™ Fluoride Aqueous Solution (experimental) on Dentin Hypersensitivity (DHS) in comparison to 3M™ Vanish™ (commercialized, control\] in patients who have DHS. Participants will be asked to complete the following activities: Undergo a pre-treatment washout period for 3- to 6-weeks (± 4 days) post-enrollment. During this time, the Subject is to only use the provided oral hygiene products. Hypersensitivity will be assessed prior to (baseline) and immediately after sample application. Subject will be asked to come to the facility for hypersensitivity assessments at 24 hours, 7 days, and 30 days after the treatment visit. Researchers will compare 3M™ Clinpro™ Fluoride Aqueous Solution to 3M™ Vanish™ to evaluate if the effect of Clinpro™ on DHS treatment is non-inferior to Vanish™.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedMar 14, 2023
Enrollment StartApr 4, 2023
Primary CompletionJul 14, 2023
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3.3 years ago

Interventions

3M™ Clinpro™ Fluoride Aqueous Solutiondevice

Hypersensitivity treatment. Apply once after baseline measurement of dentin sensitivity.

3M™ Vanish™device

Hypersensitivity treatment. Apply once after baseline measurement of dentin sensitivity.