CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 51 enrolled
Drug / intervention
Biofeedback +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05770518
NCT05770518N/ACompleted

Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion (BLiMP)

Washington University School of Medicine·interventional·Posted Mar 15, 2023·Updated Dec 22, 2025

In Brief

A clinical study evaluating Biofeedback and Laryngeal control therapy (LCT) for Paradoxical Vocal Fold Motion and Vocal Cord Dysfunction. Completed, enrolled 51 participants across 1 site.

Detailed Summary

Paradoxical Vocal Fold Motion (PVFM) is a condition where vocal cords adduct (move toward another) instead of abduct (move away from one another) during inspiration, thus causing shortness of breath. The goal of this pilot randomized controlled trial is to compare the efficacy of biofeedback as compared to laryngeal control therapy (LCT) in the treatment of PVFM. Participants will take surveys about their symptoms and their expectations of treatment prior to initiating treatment and after completion of their assigned treatment. Researchers will compare the biofeedback group to the LCT group to see if participants have differences in changes of their symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedMar 15, 2023
Enrollment StartMar 7, 2023
Primary CompletionJun 30, 2024
Study CompletionJul 30, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.3 years ago

Interventions

Biofeedbackbehavioral

Biofeedback is a strategy used in the treatment of PVFM, which involves allowing patients to directly visualize their breathing patterns during laryngoscopy.

Laryngeal control therapy (LCT)behavioral

This treatment typically involves 2 guided therapy sessions that include patient education, relaxation techniques, and training in specific breathing techniques.