CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 170 enrolled
Drug / intervention
Oxytocin (Low dose) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05782816
NCT05782816Phase 4Completed

Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor: A Randomized Control Trial

The University of Texas Medical Branch, Galveston·interventional·Posted Mar 24, 2023·Updated Jan 9, 2026

In Brief

A Phase 4 clinical trial evaluating Oxytocin (Low dose) and Oxytocin (High dose) for Labor Long. Completed, enrolled 170 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to compare oxytocin infusion rates for induction and augmentation of labor in nulliparous women. The main question\[s\] it aims to answer are: * Does a high dose oxytocin infusion protocol affect length of induction to delivery interval? * Does a high dose oxytocin infusion protocol affect mode of delivery? * Does a high dose oxytocin infusion protocol affect maternal and neonatal outcomes? Participants will be randomized to either low- or high-dose oxytocin groups: * The low dose group will receive an infusion to start at 2 milli-units/min and will be increased by 2 milli-units/min every 20 minutes. The maximum rate of infusion is 40 milli-units/min. * The high dose group will receive an infusion to start at 6 milli-units/min and will be increased by 6 milli-units/min every 20 minutes. Maximum rate of infusion is 40 milli-units/min.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLabor Long
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202420252026
First PostedMar 24, 2023
Enrollment StartApr 17, 2023
Primary CompletionDec 31, 2024
Study CompletionJun 24, 2025
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 3.3 years ago

Interventions

Oxytocin (Low dose)drug

Low dose oxytocin

Oxytocin (High dose)drug

High dose oxytocin