CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Transauricular vagus nerve stimulation (taVNS)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05801809
NCT05801809N/ACompleted

Understanding the Effects of Non-invasive Transauricular Vagus Nerve Stimulation (taVNS) on Neural Networks and Autonomic Nervous System: a Randomized Double-blind Sham-control Mechanistic Trial in Healthy Participants

Spaulding Rehabilitation Hospital·interventional·Posted Apr 6, 2023·Updated Apr 24, 2026

In Brief

A clinical study evaluating Transauricular vagus nerve stimulation (taVNS) for Healthy Volunteers. Completed, enrolled 44 participants across 1 site.

Detailed Summary

This trial aims to perform an exploratory, mechanistic, randomized double-blind sham-control trial in healthy participants to assess the physiologic effects of a single 60 minutes session of bilateral taVNS, on neural networks and autonomic function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedApr 6, 2023
Enrollment StartApr 26, 2023
Primary CompletionSep 23, 2023
Study CompletionMar 1, 2026
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 3.2 years ago

Interventions

Transauricular vagus nerve stimulation (taVNS)device

Transauricular vagus nerve stimulation (taVNS) is a simple technique in which small surface electrodes are placed over the skin of the ear that are thought to be innervated by the auricular branch of the vagus nerve (ABVN).