CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 82 enrolled
Drug / intervention
Thulium Fibre Laser +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05808257
NCT05808257N/ACompleted
CompareCT.gov

Superpulsed Thulium Fiber Laser VS. Pulse Modulated High Power Holmium:YAG Laser For Retrograde Intrarenal Surgery

Icahn School of Medicine at Mount Sinai·interventional·Posted Apr 11, 2023·Updated Jan 29, 2025

In Brief

A clinical study evaluating Thulium Fibre Laser and Holmium:Yttrium-Aluminum-Garnet for Nephrolithiasis. Completed, enrolled 82 participants across 1 site.

Detailed Summary

This is a randomized prospective study to compare stone free rates and operative efficiency of two laser systems used during retrograde intrarenal surgery for kidney stone disease: 1. A superpulsed thulium fiber laser (thulium) 2. A pulse modulated high power holmium laser (Holmium)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNephrolithiasis
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedApr 11, 2023
Enrollment StartJan 7, 2022
Primary CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 3.2 years ago

Interventions

Thulium Fibre Laserdevice

The TFL is a relatively new laser in the field of urology. First introduced on the market in 2017, it offers theoretically superior stone dusting qualities and smaller fiber sizes to allow for better irrigation.

Holmium:Yttrium-Aluminum-Garnetdevice

The Ho:YAG is currently the most commonly used laser in the field of urology and for the better part of the last 3 decades has been considered the gold standard for laser lithotripsy.