At a glance
ClinicalIndex Comparison Record- ✓Age 18 to 50 years
- ✓Healthy status
- ✓Body mass index less than 31 kg/m²
- ✓Systolic blood pressure <140 mmHg
- ✕Cardiac, respiratory, neurological, or metabolic illness
- ✕History of renal or hepatic insufficiency/disease
- ✕Pregnancy or breast feeding
- ✕Body mass less than 60 kilograms
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Intranasal Cocaine and Temperature Regulation During Exercise
In Brief
A Phase 2 clinical trial evaluating Cocaine and Lidocaine for Hyperthermia and 2 related conditions. Completed, enrolled 27 participants across 1 site.
Detailed Summary
Assess the effects of intranasal cocaine on temperature regulation and whole-body sweat rate during exercise in warm environmental conditions.
Study Details
Timeline
Interventions
Cocaine (cocaine hydrochloride 4% nasal solution) will be administered (3 mg/kg) intranasally prior to entering the warm environmental conditions and performing 60 minutes of exercise.
Lidocaine (lidocaine hydrochloride 4% nasal solution) will be administered (3 mg/kg) intranasally prior to entering the warm environmental conditions and performing 60 minutes of exercise.