CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 6 enrolled
Drug / intervention
Sodium bicarb lockdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05813535
NCT05813535Phase 2Completed
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Sodium Bicarb Locks in Intestinal Failure

Riad Rahhal·interventional·Posted Apr 14, 2023·Updated May 28, 2026

In Brief

A Phase 2 clinical trial evaluating Sodium bicarb lock for Intestinal Failure and CRBSI - Catheter Related Bloodstream Infection. Completed, enrolled 6 participants across 1 site.

Detailed Summary

We plan to include children with intestinal failure, a condition where the gut is not functioning properly, leading these children to need central venous catheters (line that goes through the skin into the blood stream) for nutritional support and hydration. Such patients have a very high risk for catheter infection. The study will include placing an agent (sodium bicarbonate) into the central catheter when the catheter is not in use. This is referred to as a lock. The lock would be used daily and removed when patients start their nutritional support and hydration through the catheter.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntestinal Failure, CRBSI - Catheter Related Bloodstream Infection
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedApr 14, 2023
Enrollment StartDec 1, 2022
Primary CompletionMar 1, 2025
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 3.2 years ago

Interventions

Sodium bicarb lockdrug

8.4% sodium bicarb locks when off venous nutrition