CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Freeze-dried Blueberry Powder +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05817383
NCT05817383N/ACompleted
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Blueberries, Gut Microbiota, and Metabolites in Depressed Older Adults - A Pilot Study

Hebrew SeniorLife·interventional·Posted Apr 18, 2023·Updated Aug 22, 2025

In Brief

A clinical study evaluating Freeze-dried Blueberry Powder and Placebo Powder for Depressive Symptoms. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This study aims to investigate the impact of daily freeze-dried blueberry powder consumption on the gut microbiota, fecal short chain fatty acids, and depressive symptom severity in 40older, sedentary adults with depressive symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepressive Symptoms
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedApr 18, 2023
Enrollment StartApr 5, 2023
Primary CompletionJul 16, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 3.2 years ago

Interventions

Freeze-dried Blueberry Powderother

Participants will be asked to consume 48 grams of freeze-dried blueberry powder (\~ equivalent to 2 cups of fresh blueberries) daily for 12 weeks. Participants will be asked to save any powder packet wrappers as a means to measure compliance. They will also be instructed to avoid consumption of foods/beverages that are high in anthocyanins and/or fiber.

Placebo Powderother

Participants will be asked to consume 48 grams of a nutritionally matched placebo powder (that does not contain fiber or anthocyanins) daily for 12 weeks. Participants will be asked to save any powder packet wrappers as a means to measure compliance. They will also be instructed to avoid consumption of foods/beverages that are high in anthocyanins and/or fiber.