CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 698 enrolled
Drug / intervention
mRNA-1011.1 +5 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05827068
NCT05827068Phase 2Completed

A Phase 1/2, Randomized, Open-Label Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults 50 to 75 Years of Age

ModernaTX, Inc.·interventional·Posted Apr 24, 2023·Updated Feb 3, 2025

In Brief

A Phase 2 clinical trial evaluating mRNA-1011.1, mRNA-1011.2, and 4 other interventions for Seasonal Influenza. Completed, enrolled 698 participants across 22 sites.

Detailed Summary

The purpose of this study is to measure the safety and the immune response to 3 next-generation influenza vaccine candidates (mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1) compared with influenza vaccine candidate mRNA-1010 controls in healthy adult participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedApr 24, 2023
Enrollment StartMar 27, 2023
Primary CompletionNov 20, 2023
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 3.2 years ago

Interventions

mRNA-1011.1biological

Sterile liquid for injection

mRNA-1011.2biological

Sterile liquid for injection

mRNA-1012.1biological

Sterile liquid for injection

mRNA-1010biological

Sterile liquid for injection

mRNA-1010.2biological

Sterile liquid for injection

mRNA-1010.3biological

Sterile liquid for injection