CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 329 enrolled
Drug / intervention
HIL-214 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05836012
NCT05836012Phase 3Completed

A Phase 2, Multi-country, Randomized, Double-blind, Placebo-controlled Trial to Evaluate Safety and Immunogenicity When HIL-214 is Concomitantly Administered With Routine Pediatric Vaccines in Healthy Infants

HilleVax·interventional·Posted May 1, 2023·Updated Mar 12, 2025

In Brief

A Phase 3 clinical trial evaluating HIL-214 and Placebo for Gastroenteritis. Completed, enrolled 329 participants across 12 sites in 3 countries.

Detailed Summary

This is a phase 2, multi-country, randomized, double-blind, placebo-controlled trial to evaluate the immune response to routine pediatric vaccinations when co-administered with HIL-214 or placebo in healthy infants. This trial will also evaluate the safety profile of a 2-dose regimen of HIL-214 co-administered with routine pediatric vaccines.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGastroenteritis
CountriesPanama, Puerto Rico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedMay 1, 2023
Enrollment StartJun 10, 2023
Primary CompletionJan 19, 2024
Study CompletionJul 8, 2024
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 3.2 years ago

Interventions

HIL-214biological

2 injections - given at 4 months and the second at 6 months of age.

Placebobiological

2 injections - given at 4 months and the second at 6 months of age.