At a glance
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Efficacy of Prabotulinum Toxin-A and Onabotulinum Toxin-A for the Treatment of Expression Lines in the Upper Third of the Face.
In Brief
A Phase 4 clinical trial evaluating Onabotulinum toxin A and Prabotulinumtoxin A for Face and 2 related conditions. Completed, enrolled 26 participants across 2 sites.
Detailed Summary
The appearance of facial wrinkles, lines, or folds is a natural phenomenon during aging. Different scales help classify wrinkles objectively, such as the Facial Wrinkle Scale. Others help classify patients' subjective perspectives, like the Face-Q questionnaire. The application of Botulinum Toxin is the most performed non-surgical aesthetic procedure in the world to treat facial expression lines. The present study aims to compare the efficacy of onabotulinum toxin-A (BOTOX®) and prabotulinum toxin-A (NABOTA®) to treat expression lines in the upper third of the face, based on objective and subjective follow-up, using the FWS scale and FACE-Q questionnaire, respectively.
Study Details
Timeline
Interventions
Intramuscular application of onabotulinum toxin-A in the upper facial third.
Intramuscular application of prabotulinum toxin-A in the upper facial third.