CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 220 enrolled
Drug / intervention
Vitamin C +1 moredrug
Likely dose
Vitamin C 1gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05842395
NCT05842395Phase 4Completed
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The Role of Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures: a Randomized Control Study

Damascus University·interventional·Posted May 6, 2023·Updated Mar 19, 2026

In Brief

A Phase 4 clinical trial evaluating Vitamin C and Placebo for Distal Radius Fracture and 2 related conditions. Completed, enrolled 220 participants across 1 site.

Detailed Summary

Complex Regional Pain Syndrome type 1 is a pain syndrome that develops after a trauma, surgery, or idiopathically. The incidence after distal radius varies significantly in the literature. There are known contributing factors, such as the female sex but no effective treatment or prophylactic method. This study aims to investigate vitamin C's efficacy in preventing CRPS type 1 following distal radius fractures, as the literature states that it might play a role in prophylaxis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDistal Radius Fracture, Vitamine c, Prophylaxis
CountriesSyria
Collaborators--

Timeline

Phase 4CompletedFinished
202420252026
First PostedMay 6, 2023
Enrollment StartJun 15, 2023
Primary CompletionMay 30, 2024
Study CompletionMar 15, 2025
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 3.2 years ago

Interventions

Vitamin Cdrug

Participants with distal radius fractures will take vitamin C supplementation with a daily dose of 1g orally for three months.

Placebodrug

Participants with distal radius fractures will take daily Placebo orally for three months.