CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 20 enrolled
Drug / intervention
Recombinant human alpha galactosidase A (agalsidase beta) +1 moredrug
Likely dose
Recombinant human alpha galactosidase A (agalsidase beta) 1 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05843916
NCT05843916Phase 3Completed

Phase III, Open-label, Switch Over Trial of the Efficacy and Safety of Agalsidase Beta Biosidus (AGA BETA BS) in Fabry Disease Patients Previously Stabilized With Fabrazyme®

Bio Sidus SA·interventional·Posted May 6, 2023·Updated Feb 18, 2026

In Brief

A Phase 3 clinical trial evaluating Recombinant human alpha galactosidase A (agalsidase beta) and Recombinant human alpha-galactosidase A (agalsidase beta) for Fabry Disease. Completed, enrolled 20 participants across 5 sites.

Detailed Summary

BIO-AGA-Fase III-001 is a Phase III, prospective, multicenter, open-label, single-group, baseline-controlled, switch over clinical trial to evaluate the efficacy and safety of AGA BETA BS in patients with FD already treated and previously stabilized with Fabrazyme®.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFabry Disease
CountriesArgentina

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedMay 6, 2023
Enrollment StartDec 13, 2022
Primary CompletionSep 19, 2024
Study CompletionMar 31, 2025
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 3.2 years ago

Interventions

Recombinant human alpha galactosidase A (agalsidase beta)drug

All participants will receive 2 doses of Fabrazyme® with approximately 14 days between them. The dose will be 1 mg/kg of body mass every 2 weeks

Recombinant human alpha-galactosidase A (agalsidase beta)drug

All participants will receive AGA BETA BS for 54 weeks. The dose will be 1 mg/kg of body mass every 2 weeks