CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 343 enrolled
Drug / intervention
Blood Pressure Control Targets +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05849103
NCT05849103N/ACompleted

Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy: A Randomized Controlled

Vanderbilt University Medical Center·interventional·Posted May 8, 2023·Updated Mar 12, 2026

In Brief

A clinical study evaluating Blood Pressure Control Targets and Hypertension Management for Hypertension, Pregnancy-Induced and 2 related conditions. Completed, enrolled 343 participants across 1 site.

Detailed Summary

Investigators propose a comprehensive management program for postpartum patients with HDP who are at risk for severe maternal morbidity and mortality. Our program will emphasize three key components: 1) self-monitoring of blood pressures with app-based reporting connected to our electronic health record, 2) blood pressure management directed by a program navigator with guideline and physician support and 3) facilitated transitions of care to primary care clinicians for hypertension management. Investigators will randomize 300 patents with HDP on postpartum day one with follow up through 3 months postpartum. Primary outcome will be blood pressure reporting at 7-10 postpartum. Secondary outcomes include blood pressure control at 7-10 days postpartum, identification and treatment of severe blood pressures, severe maternal morbidity, hospital readmission, triage visits for hypertension, postpartum and primary care visit attendance, and multiple patient-reported outcome measures. All outcomes will be stratified by race (Black and non-Black) to evaluate disparities and by tight versus usual blood pressure control to evaluate the impact of strict postpartum blood pressure control on outcomes. Investigators hypothesize that a comprehensive postpartum HDP management program will improve hypertension control for all patients and reduce disparities that affect Black patients, and that stricter blood pressure control will be associated with fewer adverse outcomes.

Study Details

Timeline

N/ACompletedFinished
202420252026
First PostedMay 8, 2023
Enrollment StartMay 8, 2023
Primary CompletionAug 1, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.1 years ago

Interventions

Blood Pressure Control Targetsother

This intervention specifies the goal blood pressure as less than 150/100 versus less than 140/90

Hypertension Managementother

This intervention specifies whether the participant has hypertension management through their obstetric clinician or through a single nurse navigator who provides feedback and modifies hypertension treatment based on blood pressure values submitted by the participant.