CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 133 enrolled
Drug / intervention
Referral for Cognitive Stimulation Therapy +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05860127
NCT05860127N/ACompleted

Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial

University of Massachusetts, Amherst·interventional·Posted May 16, 2023·Updated Mar 23, 2026

In Brief

A clinical study evaluating Referral for Cognitive Stimulation Therapy and No change to Standard of Care for Dementia and 8 related conditions. Completed, enrolled 133 participants across 2 sites.

Detailed Summary

Cognitive Stimulation Therapy (CST) is an evidence-based non-pharmacological group therapy shown to benefit people with mild to moderate dementia. Despite increasing availability of CST worldwide, access remains limited in the United States. This pilot pragmatic trial will embed CST referral into the standard care protocol of health care settings that serve people living with dementia in the state of Connecticut, and evaluate online delivery of CST known as virtual CST (V-CST), and assess the acceptability of V-CST to people living with dementia. The study design is a two-armed randomized embedded pragmatic clinical trial (ePCT). The trial aims to determine if cognitive decline is experienced less commonly among V-CST participants than control group members based on three widely used measures of cognition, the Montreal Cognitive Assessment (MoCA), St. Louis University Memory Screen (SLUMS), and Mini Mental State Exam (MMSE). The study population will be persons with mild to moderate dementia identified by clinicians in standard care. From this population, subject participants will be randomized to intervention and control groups. Patients randomly assigned to the intervention group will be referred by their clinical providers to participate in V-CST, and those who accept the referral will participate in the intervention.

Study Details

Timeline

N/ACompletedFinished
202420252026
First PostedMay 16, 2023
Enrollment StartApr 10, 2023
Primary CompletionJun 12, 2025
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 3.1 years ago

Interventions

Referral for Cognitive Stimulation Therapybehavioral

Physician will review participant eligibility for CST treatment and offer referral based on clinical judgement

No change to Standard of Careother

Participants will not receive referral from a physician. They will continue with standard of care at their site.