CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 162 enrolled
Drug / intervention
Rifaximin 550 MG +3 moredrug
Likely dose
Rifaximin 550 MGfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05867550
NCT05867550Phase 4Completed

To Compare the Efficacy of (Rifaximin + Mebeverine), (Rifaximin + Amitriptyline), and (Rifaximin + Psyllium Husk) in Irritable Bowel Syndrome Associated With Diarrhea

Bahria University·interventional·Posted May 22, 2023·Updated Jul 27, 2023

In Brief

A Phase 4 clinical trial evaluating Rifaximin 550 MG, Mebeverine 135 MG, and 2 other interventions for Irritable Bowel Syndrome With Diarrhea. Completed, enrolled 162 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to compare the efficacy of four different drugs in combination for management of irritable bowel syndrome (IBS)-associated diarrhea. The main question to answer is: * Is there a significant difference in effect of different drug combinations in management of irritable bowel syndrome with diarrhea? Participants will be divided into 3 treatment groups. * Each group will be given a combination of drugs for 2 weeks * At the end of study, efficacy of different drug combinations and their potential side effects will be compared between the treatment groups

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPakistan
Collaborators--

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedMay 22, 2023
Enrollment StartJan 3, 2023
Primary CompletionMar 27, 2023
Study CompletionJun 10, 2023
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3.1 years ago

Interventions

Rifaximin 550 MGdrug

Rifaximin 550 MG Oral Thrice Daily for 2 weeks will be included in all three treatment regimes i.e A, B and C

Mebeverine 135 MGdrug

Mebeverine 135 MG Oral Twice Daily for 2 weeks will be included in Group A Treatment Regimes

Psyllium Huskdrug

Psyllium Husk 15-35 MG Oral Once Daily for 2 weeks will be included in Group C Treatment Regimes

Amitriptyline Hydrochloride 25 MGdrug

Amitriptyline Hydrochloride 25 MG Oral Once Daily for 2 weeks will be included in Group B Treatment Regimes