CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 41 enrolled
Drug / intervention
Corticosteroid injection (CSI) with local anesthetic (LA) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05868577
NCT05868577Phase 1Completed

Infracalcaneal Peppering Injection Technique for Chronic Plantar Fasciitis: Protocol for a Parallel Randomized Clinical Trial

Wake Forest University Health Sciences·interventional·Posted May 22, 2023·Updated Oct 30, 2025

In Brief

A Phase 1 clinical trial evaluating Corticosteroid injection (CSI) with local anesthetic (LA) and Local anesthetic (LA) with Saline injection for Chronic Plantar Fasciitis. Completed, enrolled 41 participants across 1 site.

Detailed Summary

Although no single treatment has shown superiority, short-term pain relief may be offered via a targeted local corticosteroid injection (CSI), used often in combination with local anesthetic (LA), which may reduce plantar fasciitis symptoms for up to 1 month. Moreover, administering a CSI is relatively quick and easy for any Provider to perform, though it is not without potential deleterious side effects and risks, including fibroblast degradation, fat pad atrophy, skin depigmentation, and even plantar fascia rupture.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 1CompletedFinished
202420252026
First PostedMay 22, 2023
Enrollment StartOct 18, 2023
Primary CompletionSep 18, 2024
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 3.1 years ago

Interventions

Corticosteroid injection (CSI) with local anesthetic (LA)drug

The PI will then administer the injection using an infracalcaneal needle peppering

Local anesthetic (LA) with Saline injectiondrug

The PI will then administer the injection using an infracalcaneal needle peppering