CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 52 enrolled
Drug / intervention
Electronic Cigarette with 5% Nicotine Concentration +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05887947
NCT05887947N/ACompleted

Impact of E-cigarette Nicotine Concentration on Compensation, Cigarette Smoking, and Biomarkers of Exposure and Harm in Diverse Smokers

University of Kansas Medical Center·interventional·Posted Jun 5, 2023·Updated Sep 10, 2025

In Brief

A clinical study evaluating Electronic Cigarette with 5% Nicotine Concentration and Electronic Cigarette with 1.8% Nicotine Concentration for Smoking Cessation. Completed, enrolled 52 participants across 1 site.

Detailed Summary

The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an explicit focus on AA and White smokers.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202420252026
First PostedJun 5, 2023
Enrollment StartFeb 20, 2023
Primary CompletionMay 3, 2024
Study CompletionJun 10, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.1 years ago

Interventions

Electronic Cigarette with 5% Nicotine Concentrationdevice

Electronic cigarette in 5% nicotine concentration (Vuse Alto), provided for free.

Electronic Cigarette with 1.8% Nicotine Concentrationdevice

Electronic cigarette in 1.8% nicotine concentration (Vuse Alto), provided for free.