At a glance
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Stroke-induced Immunodepression: Role in the Neurorehabilitation Setting
In Brief
An observational study evaluating Neurorehabilitation for Stroke and 2 related conditions. Completed, enrolled 90 participants across 1 site.
Detailed Summary
The close interconnection between nervous system and the immune system is well known. Brain injuries lead to homeostasis disruption. On the one hand they result in increased brain inflammation contributing to tissue repair, at the expense of a possible extension of tissue damage. On the other hand, they lead to systemic down-regulation of innate and adaptive immunity, determining higher vulnerability to infections, responsible of death and comorbidities in the acute and subacute setting. Aim of the study was to evaluate the role of immunosuppression in the neurorehabilitation pathway in patients with stroke.
Study Details
Timeline
Interventions
Four to eight weeks motor rehabilitation (500 minutes per week across 6 day per week)