CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 229 enrolled
Drug / intervention
DC-806 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05896527
NCT05896527Phase 2Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-ranging Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company·interventional·Posted Jun 9, 2023·Updated Apr 4, 2025

In Brief

A Phase 2 clinical trial evaluating DC-806 and Placebo for Plaque Psoriasis. Completed, enrolled 229 participants across 56 sites in 8 countries.

Detailed Summary

This was a 12-week treatment, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study to evaluate the efficacy and safety of DC-806 in participants with moderate to severe plaque psoriasis. This study evaluated the efficacy, safety, tolerability, and pharmacokinetics (PK) of multiple oral doses of DC-806 in participants with moderate to severe plaque psoriasis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Czechia, Germany, Hungary, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedJun 9, 2023
Enrollment StartMay 2, 2023
Primary CompletionMar 25, 2024
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 3.1 years ago

Interventions

DC-806drug

DC-806 was supplied as tablets to be administered orally.

Placeboother

Matching placebo was supplied as tablets to be administered orally.