CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 2,387 enrolled
Drug / intervention
S-217622 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05897541
NCT05897541Phase 3Completed

A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of S-217622 in the Prevention of Symptomatic SARS-CoV-2 Infection in Household Contacts of an Individual With Symptomatic COVID-19

Shionogi·interventional·Posted Jun 9, 2023·Updated Aug 6, 2025

In Brief

A Phase 3 clinical trial evaluating S-217622 and Placebo for SARS-CoV-2 Infection. Completed, enrolled 2,387 participants across 178 sites in 5 countries.

Detailed Summary

The purpose of this study is to measure the proportion of participants who are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (positive reverse transcription polymerase chain reaction \[RT-PCR\] test) and have coronavirus disease 2019 (COVID-19) symptom(s) with S-217622 tablets compared with placebo tablets in participants who are household contacts of an individual with symptomatic COVID-19.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Japan, South Africa, United States, Vietnam
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedJun 9, 2023
Enrollment StartJun 9, 2023
Primary CompletionAug 30, 2024
Study CompletionSep 18, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3.1 years ago

Interventions

S-217622drug

Administered as a tablet.

Placebodrug

Administered as a tablet.