At a glance
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The Effect of Constant 5% Versus Gradient 8%, 5%, 2% Oxygen Concentration on the Development of Sibling Human Embryos in Vitro
In Brief
A clinical study evaluating Experimental intervention: 8-5-2% oxygen gradient concentration in the incubator for Embryonic Development and 2 related conditions. Completed, enrolled 44 participants across 1 site.
Detailed Summary
The purpose of this study is to investigate the development of human embryos in vitro under two different oxygen concentrations; a static 5% during all five days of culture or under an oxygen gradient, starting with 8% from day-0 to day-3, continuing with 5% on day-3 and following with 2% of oxygen from the end of day-3 to day-5.
Study Details
Timeline
Interventions
After oocyte retrieval and insemination, half of a given patient's embryos will be randomly allocated in an incubator set at a gradient of oxygen tension (8-5-2%). The embryos will remain in the incubator until their developmental assessments on day 5.