CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 88 enrolled
Drug / intervention
Probiotics +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05906381
NCT05906381N/ACompleted

A Clinical Trial of Dry Eye Symptom Mitigation by Oral Intake of Probiotics

Chung Shan Medical University·interventional·Posted Jun 15, 2023·Updated Sep 26, 2025

In Brief

A clinical study evaluating Probiotics and Placebo for Dry Eye. Completed, enrolled 88 participants across 1 site.

Detailed Summary

This study investigates whether the oral intake of a probiotics capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status. The participants will be assessed for several parameters and asked to take 1 probiotics capsule per day for 35 days. The parameters will include ocular surface health, tear volume, tear quality, intraocular pressure, tear osmolarity and serum biochemical test. After the 35 days are completed, the participants will be assessed again for the same parameters.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye
CountriesTaiwan

Timeline

N/ACompletedFinished
202420252026
First PostedJun 15, 2023
Enrollment StartMay 13, 2023
Primary CompletionAug 31, 2023
Study CompletionDec 31, 2023
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 3.0 years ago

Interventions

Probioticsdietary

A specific probiotics capsule product, containing Streptococcus thermophilus will be given to participants for oral intake for 35 days.

Placebodietary

A specific capsule product, containing microcrystalline cellulose will be given to participants for oral intake for 35 days.