CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Tranexamic Acid 100 MG/ML +1 moredrug
Likely dose
Tranexamic Acid 100 MG/MLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05919615
NCT05919615N/ACompleted
CompareCT.gov

Evaluation of Efficacy and Safety of Perioperative Tranexamic Acid During Primary Total Knee Arthroplasty: A Randomized, Clinical Trial

Damascus University·interventional·Posted Jun 26, 2023·Updated Jun 26, 2023

In Brief

A clinical study evaluating Tranexamic Acid 100 MG/ML and Normal saline for Knee Osteoarthritis and 2 related conditions. Completed, enrolled 100 participants across 1 site.

Detailed Summary

Tranexamic acid is a medication used to treat or prevent excessive blood loss during surgery. Previous studies have shown tranexamic acid (TXA) reduces blood loss and post-operative blood transfusion rate without significant complications. In addition, many meta-analyses have confirmed these results. This study also aims to determine how safe and effective tranexamic acid treatment is for different patients undergoing primary total knee arthroplasty.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis, Blood Loss, Blood Transfusion
CountriesSyria
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJun 26, 2023
Enrollment StartJul 15, 2021
Primary CompletionMar 15, 2023
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 3.0 years ago

Interventions

Tranexamic Acid 100 MG/MLdrug

Tranexamic Acid: 100 MG/ML Solution for injection

Normal salinedrug

0.9% sodium chloride normal saline