CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 110,000 target
Drug / intervention
Laminary airflowother
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05932823
NCT05932823N/ACompleted

Airflow and Hip Prosthesis Infections: A Registry Study Comparing Laminar vs. Turbulent Flow in the Danish Hip Arthroplasty Register.

University Hospital Bispebjerg and Frederiksberg·observational·Posted Jul 6, 2023·Updated Jul 6, 2023

In Brief

An observational study evaluating Laminary airflow for Hip Prosthesis Infection. Completed, enrolled 110,000 participants.

Detailed Summary

Background: During hip replacement surgery, there is a risk that bacteria in the operating room can cause an infection. To try and reduce this risk, some operating rooms use a special system called laminar airflow (LAF), which reduces the number of bacteria in the air. However, it's not clear if LAF is better than the older system, called turbulent airflow (TAF), for preventing infections. Aim: The aim of this study is to compare the two airflow systems and see if LAF is better at preventing infections after hip replacement surgery. Methods: Information from a database containing all hip replacement surgeries done in Denmark between 2010 and 2020 is examined. The number of infections that occur in surgeries done with LAF, which reduces the number of bacteria in the air during surgery, is compared to the number of infections that occur in surgeries done with TAF. To make the results more credible, the data from the hip register was combined with data from the bacterial cultures taken during surgery. Use and relevance: Infections after hip replacement surgery can be very serious and expensive to treat. Hospitals need to choose the best airflow system to help prevent these infections. This study is important because it gives more accurate information about which system is better at preventing infections and can help hospitals make better choices when they are designing or renovating operating rooms.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJul 6, 2023
Enrollment StartJan 1, 2010
Primary CompletionDec 31, 2021
TodayJul 2, 2026
Enrollment to primary: 12 yearsPosted 3.0 years ago

Interventions

Laminary airflowother

A ventilation system that reduces the number of bacteria in the air compared to conventional ventilation.