CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 24 enrolled
Drug / intervention
LTI-03 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05954988
NCT05954988Phase 1Completed

A Randomized, Double-Blind, Placebo-Controlled, Dose Escalation, Safety, Tolerability and Pharmacodynamic Biomarker Study of Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03) in Recently Diagnosed, Treatment Naïve Subjects With IPF

Rein Therapeutics·interventional·Posted Jul 20, 2023·Updated Jul 31, 2025

In Brief

A Phase 1 clinical trial evaluating LTI-03 and Placebo for Idiopathic Pulmonary Fibrosis. Completed, enrolled 24 participants across 7 sites in 3 countries.

Detailed Summary

This study will assess the safety and tolerability of inhaled LTI-03 in treatment naïve participants with newly diagnosed IPF.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, United Kingdom, United States
Collaborators--

Timeline

Phase 1CompletedFinished
202420252026
First PostedJul 20, 2023
Enrollment StartJul 6, 2023
Primary CompletionSep 25, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 2.9 years ago

Interventions

LTI-03drug

Caveolin-1-Scaffolding-Protein-Derived Peptide

Placebodrug

Matching placebo