CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled / 16 target
Drug / intervention
Sleep Restriction +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05956964
NCT05956964N/ACompletedUpdate Overdue (0.5/mo)Completion was 15mo ago
CompareCT.gov

Effects of Unloading and Sleep Restriction on Balance Regulation and Quadriceps Structure and Contractile Function

Lance Bollinger·interventional·Posted Jul 24, 2023·Updated Jun 17, 2026

In Brief

A clinical study evaluating Sleep Restriction and Sleep Adequate for Muscle Weakness and 2 related conditions. Completed, enrolled 16 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The goal of this trial is to learn about how restricted sleep and not bearing weight on the leg affects muscle strength and posture control. Participants will walk exclusively on one leg, sleep at differing intervals, and complete posture tests, muscle strength tests, and muscle imaging. Researchers will compare adequate sleep and restricted sleep to see if muscle strength and posture are affected.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMuscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
CountriesUnited States
CollaboratorsNational Aeronautics and Space Administration (NASA)

Timeline

N/ACompletedFinished
202420252026
First PostedJul 24, 2023
Enrollment StartAug 10, 2023
Primary CompletionMar 14, 2025
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 2.9 years ago

Arms & Interventions

Sleep Restriction (SR)experimental

The research team will provide participants with a pair of shoes to wear throughout the study. The right shoe will be modified to include a 5cm (approximately 2") rocker-style platform which will keep the left leg suspended during walking. Participants will also be provided with a pair of short crutches to assist with walking. Participants in the SR group will sleep only 5 hours for three consecutive nights.

Behavioral: Sleep Restriction
Sleep Adequate (SA)active_comparator

The research team will provide participants with a pair of shoes to wear throughout the study. The right shoe will be modified to include a 5cm (approximately 2") rocker-style platform which will keep the left leg suspended during walking. Participants will also be provided with a pair of short crutches to assist with walking. Participants in the SA group will sleep for 9 hours for three consecutive nights.

Behavioral: Sleep Adequate

Interventions

Sleep Restrictionbehavioral

5 hours of sleep for 3 days

Sleep Adequatebehavioral

9 hours of sleep for 3 days