CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,104 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT05958576
NCT05958576N/ACompleted

Effect of Age on Sperm Recovery of Microdissection Testicular Sperm Extraction in Nonobstructive Azoospermia Patients

Peking University Third Hospital·observational·Posted Jul 24, 2023·Updated Jul 24, 2023

In Brief

An observational study for Non-obstructive Azoospermia. Completed, enrolled 3,104 participants across 1 site.

Detailed Summary

Males with non-obstructive azoospermia (NOA) have an opportunity to obtain sperm by treatment with microdissection testicular sperm extraction (mTESE), gold-standard surgical technique for them. The overall sperm retrieval rate (SRR) of mTESE in NOA patients is about 50%, but the predictive factors of SRR remain were understudied, especially the effect of age. The purpose of this study was to explore the factors influencing the SRR of mTESE in NOA patients with different etiologies. Methods: This observational study recruit NOA patients treated with their first mTESE. The stratified research was used to investigate SRR by dividing patients into seven groups based on etiology. The primary outcome was SRR. Multivariable logistic regression was used to analyze the factors influencing SRR.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJul 24, 2023
Enrollment StartMar 1, 2012
Primary CompletionDec 31, 2022
Study CompletionMar 31, 2023
TodayJul 2, 2026
Enrollment to primary: 10.8 yearsPosted 2.9 years ago