CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 98 enrolled
Drug / intervention
Diuretics withdrawal +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05964738
NCT05964738Phase 2Completed
CompareCT.gov

Safety and Tolerability of Diuretics Withdrawal in Heart Failure With Reduced Ejection Fraction. REDICAE Trial.

Maimónides Biomedical Research Institute of Córdoba·interventional·Posted Jul 28, 2023·Updated Nov 4, 2024

In Brief

A Phase 2 clinical trial evaluating Diuretics withdrawal and Diuretics maintenance for Heart Failure and 4 related conditions. Completed, enrolled 98 participants across 1 site.

Detailed Summary

REDICAE trial was designed to evaluate the safety and tolerability of diuretics withdrawal in stable, euvolemic chronic outpatients with heart failure with reduced ejection fraction. It is a single-center, randomized, open-label, phase II clinical trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure, Electric Impedance, Dyspnea, Safety, Withdrawal
CountriesSpain
CollaboratorsSociedad Andaluza de Cardiología

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedJul 28, 2023
Enrollment StartDec 19, 2022
Primary CompletionOct 31, 2024
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 2.9 years ago

Interventions

Diuretics withdrawaldrug

Diuretics that not have been demonstrated improve survival in chronic HFrEF are withdrawn

Diuretics maintenancedrug

Any diuretic could be used