CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 530 enrolled
Drug / intervention
RSVPreF3 OA investigational vaccine +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05966090
NCT05966090Phase 3Completed

A Phase III, Open-label, Randomized, Controlled, Multi-country Study to Evaluate the Immune Response, Safety and Reactogenicity of RSVPreF3 OA Investigational Vaccine When Co-administered With Herpes Zoster Recombinant Subunit (HZ/su) Vaccine in Adults Aged 50 Years and Older

GlaxoSmithKline·interventional·Posted Jul 28, 2023·Updated Apr 1, 2025

In Brief

A Phase 3 clinical trial evaluating RSVPreF3 OA investigational vaccine and HZ/su vaccine for Respiratory Syncytial Viruses and Respiratory Syncytial Virus Infections. Completed, enrolled 530 participants across 31 sites in 2 countries.

Detailed Summary

To assess the ability of RSVPreF3 OA investigational vaccine to generate an immune response when given in combination with HZ/su vaccine and its safety in older adults, aged \>=50 years of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedJul 28, 2023
Enrollment StartJul 28, 2023
Primary CompletionFeb 19, 2024
Study CompletionJul 29, 2024
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 2.9 years ago

Interventions

RSVPreF3 OA investigational vaccinebiological

One dose of RSVPreF3 OA investigational vaccine given intramuscularly on Day 1 (Coadministration group) or Day 31 (Control group).

HZ/su vaccinebiological

Two doses of HZ/su vaccine given intramuscularly on Day 1 and Day 61.