CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 405 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05969886
NCT05969886N/ACompleted

Predictive Value of Ventricular-Arterial Coupling for Post-Induction Hypotension: A Prospective Observational Cohort Study

University Medical Center Ho Chi Minh City (UMC)·observational·Posted Aug 1, 2023·Updated Dec 30, 2024

In Brief

An observational study for Hypotension on Induction. Completed, enrolled 405 participants across 1 site.

Detailed Summary

Post-induction hypotension (PIH) is a common occurrence during the period from induction of general anesthesia to initiation of incision. PIH has been identified as an independent risk factor for postoperative major complications. Identifying high-risk patients for PIH could potentially help prevent its occurrence. Several risk factors associated with PIH have been identified, including patient conditions and use of specific anesthetic agents. Ventricular-arterial coupling (VAC) is evaluated using the ratio Ea/Ees and represents the interaction between the left ventricle (LV) and the arterial system. It reflects how changes in LV contractility (Ees) and changes in arterial load (Ea) work together to maintain optimal LV performance. A study aims to investigate the relationship between preoperative Ea/Ees ratio and the incidence of PIH (defined as MAP \< 65 mmHg).

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesVietnam
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 1, 2023
Enrollment StartJul 3, 2023
Primary CompletionNov 20, 2024
Study CompletionDec 10, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 2.9 years ago