CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 518 enrolled
Drug / intervention
FLU Q-PAN H5N8 375_B +3 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05975840
NCT05975840Phase 2Completed

A Phase I/II Observer-blind, Randomized, Multi-center Trial to Evaluate the Safety and Immunogenicity of Different Formulations of Monovalent Influenza A/Astrakhan/3212/2020 Like (H5N8) Virus Vaccine With AS03 Adjuvant System (Referred to as Q-Pan H5N8), Given as a Two-dose Series to Adults 18 to 64 Years of Age and 65 Years of Age and Older

GlaxoSmithKline·interventional·Posted Aug 4, 2023·Updated Aug 19, 2025

In Brief

A Phase 2 clinical trial evaluating FLU Q-PAN H5N8 375_B, FLU Q-PAN H5N8 375_A, and 2 other interventions for Influenza, Human. Completed, enrolled 518 participants across 20 sites.

Detailed Summary

The purpose of this study is to assess the safety and immunogenicity of different formulations of monovalent Influenza A/Astrakhan/3212/2020-like virus vaccine with AS03 adjuvant system in adults greater than or equal to (\>=)18 years of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedAug 4, 2023
Enrollment StartAug 3, 2023
Primary CompletionMay 21, 2024
Study CompletionSep 19, 2024
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 2.9 years ago

Interventions

FLU Q-PAN H5N8 375_Bbiological

Participants received 2 doses of 375\_B vaccine formulation by intramuscular injection in the non-dominant arm.

FLU Q-PAN H5N8 375_Abiological

Participants received 2 doses of 375\_A vaccine formulation by intramuscular injection in the non-dominant arm.

FLU Q-PAN H5N8 750_Bbiological

Participants received 2 doses of 750\_B vaccine formulation by intramuscular injection in the non-dominant arm.

FLU Q-PAN H5N8 750_Abiological

Participants received 2 doses of 750\_A vaccine formulation by intramuscular injection in the non-dominant arm.