CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 493 enrolled
Drug / intervention
CHECKIT!other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05977881
NCT05977881N/ACompleted

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

Johns Hopkins Bloomberg School of Public Health·interventional·Posted Aug 7, 2023·Updated May 14, 2026

In Brief

A clinical study evaluating CHECKIT! for HIV Infections. Completed, enrolled 493 participants across 1 site.

Detailed Summary

Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an overdose prevention and HIV prevention study among people who use drugs (PWUD). Specifically, SCOPE will provide access to drug-checking services for PWUD to better understand the contents of the drug supply, in combination with PrEP for those who are HIV-, to both reduce overdose and HIV among PWUD in Baltimore City.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections
CountriesUnited States

Timeline

N/ACompletedFinished
202420252026
First PostedAug 7, 2023
Enrollment StartJul 28, 2023
Primary CompletionMay 1, 2026
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 2.9 years ago

Interventions

CHECKIT!other

Participants will not be assigned to the intervention as it will be available to everyone. Check it will be a van-based HIV- and overdose-prevention program offered in the four areas of Baltimore city from which study participants are recruited. Intervention services will include point-of-care drug checking and PrEP assessment, prescription, and management, and they will be available to everyone, regardless of whether they are part of the SCOPE study cohort or not. Individual-level service usage data collected by intervention staff will not be considered in analysis of outcomes. However, study participants will self-report Check it utilization on the internally-developed surveys at 6, 12, and 18 months.