CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled / 14 target
Drug / intervention
iTBSdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05985356
NCT05985356N/ACompletedUpdate Overdue (0.4/mo)Completion was 14mo ago
CompareCT.gov

Neuromodulation for Comorbid Hoarding Disorder and Depression

University of California, San Diego·interventional·Posted Aug 14, 2023·Updated Jun 17, 2026

In Brief

A clinical study evaluating iTBS for Hoarding Disorder and 2 related conditions. Completed, enrolled 14 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The primary goal of this study is to evaluate whether intermittent theta burst stimulation (iTBS) is effective for treating depression in people who have depression and chronic hoarding disorder (HD). The study will also evaluate whether this treatment can improve HD symptoms, cognitive performance, and brain region connectivity. The study team will investigate how the treatment works for depression, as well as other factors that can enhance or hinder treatment, such as pre-treatment level of depression, cognitive performance, or brain region connectivity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHoarding Disorder, Hoarding, Depression
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 14, 2023
Enrollment StartAug 28, 2023
Primary CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 2.9 years ago

Arms & Interventions

iTBSexperimental

intermittent Theta Burst Stimulation (a form of transcranial magnetic stimulation) targeting the left dorsolateral prefrontal cortex

Device: iTBS

Interventions

iTBSdevice

iTBS targeting the left dorsolateral prefrontal cortex; 20 sessions over 4 weeks.