CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 546 enrolled
Drug / intervention
Zoll external defibrillator +1 moredevice
Likely dose
Zoll: 200J synchronized shock with rectilinear biphasic waveform; Lifepak: 360J synchronized shock with biphasic truncated exponential waveformAI-extracted
Key inclusion· 2
  • Age 18 years or older
  • Atrial fibrillation on presentation with planned direct current cardioversion
Key exclusion· 6
  • Arrhythmias other than atrial fibrillation
  • Hemodynamically unstable atrial fibrillation
  • Untreated hyperthyroidism
  • Known or suspected pregnancy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05992623
NCT05992623N/ACompleted

A Pragmatic Randomized Clinical Trial Comparing Rectilinear Biphasic Waveform and Biphasic Truncated Exponential Waveform Shocks for Cardioversion of Atrial Fibrillation (Zoll vs Lifepak)

Inova Health Care Services·interventional·Posted Aug 15, 2023·Updated Sep 22, 2025

In Brief

A clinical study evaluating Zoll external defibrillator and Lifepak external defibrillator for Atrial Fibrillation. Completed, enrolled 546 participants across 1 site.

Detailed Summary

The goal of this single center, investigator initiated, open label prospective randomized controlled trial is to compare the efficacy of a single 200J RBW shock and a single 360J BTE shock. The secondary objective of the study is to compare the frequency of adverse events after one or two 200J RBW or 360J BTE shocks

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedAug 15, 2023
Enrollment StartJul 21, 2023
Primary CompletionAug 14, 2024
Study CompletionDec 11, 2024
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 2.9 years ago

Interventions

Zoll external defibrillatordevice

Patients with AF will be randomized to receive a full output synchronized 200J shock using a RBW waveform from a Zoll defibrillator

Lifepak external defibrillatordevice

Patients with AF will be randomized to receive a full output synchronized 360J shock using a BTE waveform from a Lifepak defibrillator